Article Abstract

Sheffield 2nd International Workshop on experimental studies of nephrogenic systemic fibrosis, 15th June 2012, Sheffield, UK

Authors: Sameh K Morcos

Abstract

A group of experienced researchers in the field of experimental studies investigating the condition nephrogenic systemic fibrosis (NSF) were invited for a workshop to share knowledge, and consolidate the current understanding of the pathophysiology of this complication associated with the administration of gadolinium based contrast agents (GBCAs) in patients with advanced renal impairment. The workshop started with a session on the diagnostic criteria and epidemiology of NSF. This was followed by a session on in vitro studies using fibroblasts followed by a session on in vivo experimental studies employing different animal models. The work shop was finished with discussing the safety of using macrocyclic GBCAs in patients suffering from NSF.