Posterior cortical atrophy: the value of neuroimaging in assessing memory loss

Posterior cortical atrophy (PCA) is a clinico-radiologic syndrome characterized by progressive decline in visual processing skills (1). Although PCA is regarded as a subgroup of Alzheimer’s disease (AD), it is associated with the following “atypical” features which differentiate it from AD including: (I) younger age at onset of 50–65 years; (II) topographic distributions of atrophy and decreased metabolic activity in the posterior cortex (2,3).