TY - JOUR AU - Baghaie, Ahmadreza AU - Yu, Zeyun AU - D’Souza, Roshan M. PY - 2015 TI - State-of-the-art in retinal optical coherence tomography image analysis JF - Quantitative Imaging in Medicine and Surgery; Vol 5, No 4 (August 24, 2015): Quantitative Imaging in Medicine and Surgery Y2 - 2015 KW - N2 - Optical coherence tomography (OCT) is an emerging imaging modality that has been widely used in the field of biomedical imaging. In the recent past, it has found uses as a diagnostic tool in dermatology, cardiology, and ophthalmology. In this paper we focus on its applications in the field of ophthalmology and retinal imaging. OCT is able to non-invasively produce cross-sectional volumetric images of the tissues which can be used for analysis of tissue structure and properties. Due to the underlying physics, OCT images suffer from a granular pattern, called speckle noise, which restricts the process of interpretation. This requires specialized noise reduction techniques to eliminate the noise while preserving image details. Another major step in OCT image analysis involves the use of segmentation techniques for distinguishing between different structures, especially in retinal OCT volumes. The outcome of this step is usually thickness maps of different retinal layers which are very useful in study of normal/diseased subjects. Lastly, movements of the tissue under imaging as well as the progression of disease in the tissue affect the quality and the proper interpretation of the acquired images which require the use of different image registration techniques. This paper reviews various techniques that are currently used to process raw image data into a form that can be clearly interpreted by clinicians. UR - https://qims.amegroups.org/article/view/7017