TY - JOUR AU - Reif, Roberto AU - Zhi, Zhongwei AU - Dziennis, Suzan AU - Nuttall, Alfred L. AU - Wang, Ruikang K. PY - 2013 TI - Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry JF - Quantitative Imaging in Medicine and Surgery; Vol 3, No 5 (October 12, 2013): Quantitative Imaging in Medicine and Surgery Y2 - 2013 KW - N2 - In this work we determined the contributions of loud sound exposure (LSE) on cochlear blood flow (CoBF) in an in vivo anesthetized mouse model. A broadband noise system (20 kHz bandwidth) with an intensity of 119 dB SPL, was used for a period of one hour to produce a loud sound stimulus. Two techniques were used to study the changes in blood flow, a Doppler optical microangiography (DOMAG) system; which can measure the blood flow within individual cochlear vessels, and a laser Doppler flowmetry (LDF) system; which averages the blood flow within a volume (a hemisphere of ~1.5 mm radius) of tissue. Both systems determined that the blood flow within the cochlea is reduced due to the LSE stimulation. UR - https://qims.amegroups.org/article/view/2909