@article{QIMS27253,
author = {Min Zhang and Lihao Sun and Weiwei Rui and Rui Guo and Huihui He and Ying Miao and Hongping Meng and Jianmin Liu and Biao Li},
title = {Semi-quantitative analysis of 99m Tc-sestamibi retention level for preoperative differential diagnosis of parathyroid carcinoma},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {9},
number = {8},
year = {2019},
keywords = {},
abstract = {Background: To investigate the role of 99mTc-labeled sestamibi (99mTc-MIBI) retention level in the assessment of malignant potential of parathyroid lesions.
Methods: Twenty patients with parathyroid carcinomas and forty controls with benign parathyroid lesions who underwent preoperatively 99mTc-MIBI dual-phase planar and SPECT/CT imaging were retrospectively enrolled in this study. The mean and peak of retention index (RImean and RIpeak) were measured for evaluating the retention level of 99mTc-MIBI in the parathyroid lesions. Diagnostic accuracies of RI for differentiating malignant parathyroid lesions from benign ones were assessed by receiver operating characteristic analyses (area under the curve; AUC).
Results: RIpeak (AUC =0.87, P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/27253}
}