TY - JOUR AU - Tang, Meng Yue AU - Chen, Tian Wu AU - Huang, Xiao Hua AU - Li, Xing Hui AU - Wang, Si Yue AU - Liu, Nian AU - Zhang, Xiao Ming PY - 2016 TI - Acute pancreatitis with gradient echo T2*-weighted magnetic resonance imaging JF - Quantitative Imaging in Medicine and Surgery; Vol 6, No 2 (April 28, 2016): Quantitative Imaging in Medicine and Surgery Y2 - 2016 KW - N2 - Background: To study gradient recalled echo (GRE) T2*-weighted imaging (T2*WI) for normal pancreas and acute pancreatitis (AP). Methods: Fifty-one patients without any pancreatic disorders (control group) and 117 patients with AP were recruited. T2* values derived from T2*WI of the pancreas were measured for the two groups. The severity of AP was graded by the magnetic resonance severity index (MRSI) and the Acute Physiology and Chronic Healthy Evaluation II (APACHE II) scoring system. Logistic regression was used to analyze the relationship between the T2* values and AP. The usefulness of the T2* value for diagnosing AP and the relationship between the T2* values and the severity of AP were also analyzed. Results: On GRE-T2*WI, the normal pancreas showed a well-marinated and consistently homogeneous isointensity. Edematous AP, as well as the non-necrotic area in necrotizing AP, showed ill-defined but homogeneous signal intensity. AP with pancreatic hemorrhage showed a decreased T2* value and a signal loss on the signal decay curve. The T2* value of pancreas in the AP group was higher than that of the control group (t=−8.20, P 0.05). AP was associated with a one standard deviation increment in the T2* value (OR =1.37; 95% CI: 1.216–1.532). Conclusions: T2*WI demonstrates a few characteristics of the normal pancreas and AP, which could potentially be helpful for detecting hemorrhage, and contributes to diagnosing AP and its severity. UR - https://qims.amegroups.org/article/view/10198