Article Abstract

Ultrasound imaging in nonalcoholic liver disease: current applications and future developments

Authors: Kuen Cheh Yang, Yin-Yin Liao, Po-Hsiang Tsui, Chih-Kuang Yeh


In 1980, Ludwig described non-alcoholic liver disease (NAFLD) in patients who did not drink alcohol, but whose liver histology showed alcoholic-like liver disease (1). NAFLD includes a range of diseases from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH). The prevalence of NAFLD is highest in the Middle East (31.8%), followed by Asia (27.4%), USA (24.1%) and Europe (23.7%), to the lowest (13.5%) in Africa (2). Accordingly, NAFLD has emerged as the most common chronic liver disease worldwide. The overall global economic burden increases as the clinical consequences of NAFLD grow, including liver-specific, cardiovascular disease and overall mortality (3). Compared to the effective anti-viral treatments for viral chronic hepatitis, the management of NAFLDs is still under development. Although there is no universal consensus, many scientific communities have developed guidelines for diagnosis and treatment.

Article Options

Download Citation