What is changed in the diagnosis of osteoporosis: the role of radiologists

Giuseppe Guglielmi, Rosario Francesco Balzano, Xiaoguang Cheng


Osteoporosis (OP) is a very common condition with several repercussions on patients’ quality of life and health systems (1). OP is secondary to changes in normal bone turnover for decreased activity of osteoblasts (which produce bone matrix) or increased osteoclastic activity (2,3). These changes determine variation in bone mineral content (BMC) and then bone mineral density (BMD); thus, quantification of BMD correlate to changes in bone matrix.