Acute myocardial infarction and stroke secondary to valve thrombosis following transcatheter aortic valve replacement—what can happen when antiplatelet agents are stopped

Mau Chu Lam, Gajen Kanaganayagam, Yousif Ahmad, Michael Fertleman, Ben Ariff


An 84-year-old woman was hospitalised for a fall with subsequent agitation and vomiting. She had a past medical history of coronary artery bypass grafting performed 18 years ago. In the 8 months prior to her admission, she underwent transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS). Post procedure, the patient had been instructed to take dual antiplatelet therapy (DAPT) for 6 months but had stopped these herself earlier than the recommendation.