Left ventricular ‘rigid body rotation’ in a patient with acromegaly (from the MAGYAR-Path Study)

Attila Nemes, Árpád Kormányos, Péter Domsik, Anita Kalapos, Csaba Lengyel, Zsuzsanna Valkusz, Tamás Forster

Abstract

Cardiovascular complications are known features in acromegaly due to growth hormone (GH) and insulin-like growth factor 1 (IGF-1) excess (1,2). In healthy subjects, left ventricular (LV) apex and base rotate in opposite directions resulting in a towel-wringing-like motion called as LV twist, which could be easily and non-invasively quantified by three-dimensional (3D) speckle-tracking echocardiography (3DSTE) (3). However, little is known about LV myocardial rotational mechanics in acromegaly.